SUMMARY Multiple sclerosis (MS) is the most common CNS-demyelinating disease of humans, showing clinical and pathological heterogeneity and a general resistance to therapy.We first discovered that abnormal myelin hypercitrullination, even in normal-appearing white matter, by peptidylarginine deiminases (PADs) correlates strongly with disease severi

The new logistics landscape needs openness, efficiency, and agility.Conventional tracking techniques are unable to keep up with the complex dance of items traveling across countries.Intelligent and communicative smart sensors have changed the game by allowing for real-time process monitoring and revolutionizing the logistics process from start to f

The quality of feedstock used in base oil processing depends on the source of the crude oil.Moreover, the refinery is fed with various blends of crude oil to meet the demand of the refining products.These circumstances have caused changes of quality of the feedstock for the base oil production.Often the feedstock properties deviate from the origina

For Dostoevsky at the beginning of philosophy there is the mystical tremor canon imageclass mf227dw not the wonder.The tremor is not fear or torment, but the wound of our weak human condition.Is a sign of our ontological dependence.In Crime and Punishment, the term tremor occurs many times.It breaks the closure of the self and reveals the need for

Background: Most of the non steroidal anti-inflammatory drugs are not equally effective in all inflammatory conditions especially in chronic conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.Hence there is a need for newer and safer non steroidal anti-inflammatory drugs directed against cell adhesion molecules are bein